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Nicotine dependence represents a persistent, relapsing medical condition that creates substantial challenges for healthcare systems worldwide. Primarily driven by compulsive tobacco product use—especially cigarettes and smokeless tobacco—this addiction affects millions globally and correlates with serious health complications including heart disease, lung disorders, and various...

The Stockade Bobcat in GTA 5, officially known as the Brute Bobcat Security Stockade, is a commercial armored truck recently introduced in GTA Online as part of the 1.71 Money Fronts update. Although originally cut from the GTA 5 story mode GTA 5 Modded Accounts, it made its debut in the online multiplayer version and quickly gained attention for its rugged design and utility. The vehicle is...

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Mucopolysaccharidosis Type I (MPS I) is a rare, inherited lysosomal storage disorder caused by mutations in the IDUA gene, which encodes the enzyme alpha-L-iduronidase. This enzyme is responsible for breaking down glycosaminoglycans (GAGs), including dermatan sulfate and heparan sulfate. In MPS I, deficiency or absence of alpha-L-iduronidase leads to progressive accumulation of GAGs in various...