Mitogen-Activated Protein Kinase Inhibitors: Transforming Targeted...

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2025-11-07 04:03:40

Mitogen-Activated Protein Kinase Inhibitors: Transforming Targeted Cancer Therapy

Understanding the MAPK Pathway The Mitogen-Activated Protein Kinase (MAPK) pathway is a key signaling cascade that regulates critical cellular processes such as growth, differentiation, stress responses, and apoptosis. Central to this pathway are three kinases—RAF, MEK, and ERK—which relay signals from external stimuli like growth factors or oncogenic mutations. Aberrant...

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