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Catechol-O-Methyltransferase Inhibitors: Mechanism, Applications, and Market Trends
Catechol-O-methyltransferase (COMT) inhibitors are a critical category of drugs in neurology and pharmacology, acting by suppressing the activity of catechol-O-methyltransferase, the enzyme responsible for breaking down neurotransmitters such as dopamine, epinephrine, and norepinephrine. By slowing the breakdown of these compounds, COMT inhibitors enhance dopaminergic signaling in the brain,...
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