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Fabry disease is a rare, X-linked lysosomal storage disorder caused by mutations in the GLA gene, leading to a deficiency of the enzyme alpha-galactosidase A (α-Gal A). This enzyme is responsible for breaking down globotriaosylceramide (GL-3 or Gb3), a complex lipid. Enzyme deficiency results in systemic accumulation of Gb3 and related glycosphingolipids, particularly in vascular...
Introduction LED lighting systems are widely used for aviation purposes by the aircraft industry through advanced light-emitting diode (LED) technology for interior as well as exterior illumination. The modern illumination system substitutes traditional incandescent and fluorescent lighting with lighting fixtures that bring high energy efficiency, extended operational time, and superior...