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Niemann-Pick Type C (NPC) is a rare, autosomal recessive lysosomal storage disorder marked by defective intracellular lipid trafficking. Characterized by progressive neurodegeneration, hepatosplenomegaly, and ataxia, NPC is driven by mutations in the NPC1 (95%) or NPC2 (5%) genes. These defects impair cholesterol and glycosphingolipid transport, leading to their accumulation within cells,...

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Introduction Streetwear has taken over the fashion world in recent years, and one of the standout names leading this movement is Fear of God Essentials. Known for its minimalist designs, neutral color palettes, and high-quality fabrics, the Essentials hoodie has become a must-have piece in the UK’s fashion scene. From London’s busy streets to university campuses and music...

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